Regulatory T-Cells Support Stem Cell Therapy in Safe Minimization of Immunosuppression in Living Donor Renal Transplantation
نویسندگان
چکیده
1Department of Nephrology, Transplantation Medicine and Immunology, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases & Research Centre [IKDRC],Ahmedabad, Gujarat, India 2Department of Pathology, Laboratory Medicine, Transfusion Services, Immunohematology, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases & Research Centre [IKDRC],Ahmedabad, Gujarat, India 3Senior Research Officer, Stem Cell lab, Transplantation Biology Research Centre, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases & Research Centre [IKDRC],Ahmedabad, Gujarat, India
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Evaluation of Therapeutic Effects of Autologous Bone Marrow Mesenchymal Stem Cells to Prevent the Progression of Chronic Nephropathy in Renal Transplant
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BACKGROUND/OBJECTIVE We designed a clinical trial on a group of live-donor renal transplantation (LDRT) patients subjected to pre-transplant stem cell transplantation (SCT) to minimize immunosuppression to low-dose steroid monotherapy. METHODS LDRT patients subjected to pretransplant SCT who had stable graft function for ≥2 years and serum creatinine (SCr) <2 mg/dL were recruited. Patients wi...
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